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Table 3 Rates of d N and d S substitutions in the ABSs and non-ABSs of wolf MHC I genes

From: Characterization of the peripheral blood transcriptome and adaptive evolution of the MHC I and TLR gene families in the wolf (Canis lupus)

  N d N d S Z p -2lnΔL PAML M8
MHC I ALL sites 181 or 182 14.5 (1.5) 10.2 (1.4) 2.304 0.023 104.28** 44, 61, 65, 66, 72, 73, 95, 97, 99, 114, 116, 138, 152, 156, 157
ABS 29 41.6 (8.7) 20.0 (6.2) 2.69 0.008
Non-ABS 152 or 153 10.6 (1.3) 8.6 (1.4) 1.063 0.29
DLA-12 All sites 181 0.9 (0.3) 0 2.834 0.005 14.15** 49, 51, 61, 114, 116, 127, 141, 154
ABS 29 0.6 (0.5) 0 1.013 0.313
Non-ABS 152 0.9 (0.3) 0 2.66 0.009
DLA-88 All sites 182 4.8 (1.0) 2.1 (0.6) 2.67 0.009 81.47** 61, 65, 66, 72, 95, 97, 114, 116, 138, 152, 157
ABS 29 21.8 (6.4) 6.6 (2.7) 3.12 0.002
Non-ABS 153 2.7 (0.7) 1.6 (0.6) 1.17 0.245
  1. N is the number of codons in each category. The d N and d S values are given as the percentage per site. The standard errors in parentheses were computed using 1000 bootstrap replicates. The inferred positively selected codons located at ABSs are underlined. Significant results are highlighted in bold. **p < 0.01