Comprehensive proteome profiling in Aedes albopictus to decipher Wolbachia-arbovirus interference phenomenon

BMC Genomics

Table 1 Profiling of protein accumulation

Profile		Profile name	Time	wAlbB	CHIKV	Bi-infection	Number of spots	Network
Mono Infection	Wolbachia	W_Up_1	24 h	Up	ø	Up	13
		W_Up_2	120 h	Up	ø	Up	5
		W_Down_1	24 h	Down	ø	Down	7
		W_Down_2	120 h	Down	ø	Down	2
	CHIKV	V_Down	24 h	ø	Down	Down	1
Dominance	Wolbachia dominance	W_DOM_1	24 h	ø	Up	ø	1	Fig. 5a
		W_DOM_2	24 h	Up	Down	Up	2	Fig. 5b
		W_DOM_3	24 h	ø	Down	ø	1	Fig. 5c
		W_DOM_4	120 h	Down	Up	Down	12	Fig. 5d
	CHIKV Dominance	V_DOM_1	120 h	Up	ø	ø	2	Not Shown
		V_DOM_2	120 h	Up	Down	Down	1	Fig. 6a
		V_DOM_3	120 h	Down	Up	Up	2	Fig. 6b
Cumulative		CUMUL_1	24 h	Down	Down	Down	3	Fig. 7a
Cumulative		CUMUL_2	120 h	Up	Up	Up	1	Fig. 7b
Interference		INT_1	24 h	Down	Down	Up	1	Fig. 8d
		INT_2	24 h	ø	Down	Up	1	Fig. 8a
		INT_3	120 h	Down	Up	ø	5	Fig. 8b
		INT_4	120 h	Down	Down	ø	1	Fig. 8c
		INT_5	120 h	Up	ø	Down	1	Fig. 8e

All profiles were normalized with respect to uninfected modality. Effective observed fold changes are reported on Additional file 1: Table S1. In comparison to uninfected C6/36 cells: Up: A positive difference on protein synthesis has been observed; Down: A negative difference on proteins synthesis has been observed; ø: No difference has been observed

ISSN: 1471-2164