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Table 1 Results of the Advaita Bio’s iPathwayGuide pathway analysis based on the list of genes that are differentially expressed (q-value <0.05 and |fold-change| > 1.5) in the porcine gluteus medius muscle before (T0) vs 5 h (T1) and 7 h (T2) after eating

From: Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle

T0 vs T1 T0 vs T2 T1 vs T2
Pathway P-value Pathway P-value Pathway P-value
Circadian rhythm 1.00E-03 Ribosomea 4.97E-06 Ribosomea 2.84E-13
Circadian entrainment 4.00E-03 Circadian rhythm 8.48E-04 Huntington’s disease 2.84E-04
Cholinergic synapse 4.00E-03 Huntington’s disease 1.00E-03 Parkinson’s disease 7.33E-04
Adrenergic signaling in cardiomyocytes 4.00E-03 Legionellosis 5.00E-03 Oxidative phosphorylationa 8.74E-04
Transcriptional misregulation in cancer 7.00E-03 Parkinson’s disease 6.00E-03 Alzheimer’s disease 1.00E-03
TGF-β signaling pathway 1.30E-02 Viral myocarditis 7.00E-03 Tight junction 1.30E-02
GABAergic synapse 1.50E-02 Malaria 7.00E-03 Metabolic pathwaysa 1.80E-02
Malaria 1.60E-02 p53 signaling pathway 1.00E-02 Herpes simplex infection 1.80E-02
Cardiac muscle contractiona 2.40E-02 Alzheimer’s disease 1.10E-02 p53 signaling pathway 2.50E-02
Herpes simplex infection 2.70E-02 Mineral absorption 1.30E-02 Viral myocarditis 2.90E-02
Fructose and mannose metabolisma 3.20E-02 Toxoplasmosis 1.50E-02 Legionellosis 3.20E-02
Neuroactive ligand-receptor interaction 3.20E-02 PPAR signaling pathway 1.90E-02 Amyotrophic lateral sclerosis (ALS) 3.20E-02
Dopaminergic synapse 3.30E-02 Amyotrophic lateral sclerosis (ALS) 2.20E-02 Sulfur metabolisma 3.60E-02
Alanine, aspartate and glutamate metabolisma 3.50E-02 Sulfur metabolisma 2.40E-02 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5.00E-02
Glutamatergic synapse 3.60E-02 African trypanosomiasis 2.50E-02   
Estrogen signaling pathway 3.70E-02 Transcriptional misregulation in cancer 2.90E-02   
Bladder cancer 4.10E-02 Cardiac muscle contractiona 3.30E-02   
Dilated cardiomyopathy 4.90E-02 Tight junction 4.90E-02   
  1. athe P-value corresponding to the pathway was computed using only over-representation analysis