Table 1 Results of the Advaita Bio’s iPathwayGuide pathway analysis based on the list of genes that are differentially expressed (q-value <0.05 and |fold-change| > 1.5) in the porcine gluteus medius muscle before (T0) vs 5 h (T1) and 7 h (T2) after eating
From: Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
T0 vs T1 | T0 vs T2 | T1 vs T2 | |||
|---|---|---|---|---|---|
Pathway | P-value | Pathway | P-value | Pathway | P-value |
Circadian rhythm | 1.00E-03 | Ribosomea | 4.97E-06 | Ribosomea | 2.84E-13 |
Circadian entrainment | 4.00E-03 | Circadian rhythm | 8.48E-04 | Huntington’s disease | 2.84E-04 |
Cholinergic synapse | 4.00E-03 | Huntington’s disease | 1.00E-03 | Parkinson’s disease | 7.33E-04 |
Adrenergic signaling in cardiomyocytes | 4.00E-03 | Legionellosis | 5.00E-03 | Oxidative phosphorylationa | 8.74E-04 |
Transcriptional misregulation in cancer | 7.00E-03 | Parkinson’s disease | 6.00E-03 | Alzheimer’s disease | 1.00E-03 |
TGF-β signaling pathway | 1.30E-02 | Viral myocarditis | 7.00E-03 | Tight junction | 1.30E-02 |
GABAergic synapse | 1.50E-02 | Malaria | 7.00E-03 | Metabolic pathwaysa | 1.80E-02 |
Malaria | 1.60E-02 | p53 signaling pathway | 1.00E-02 | Herpes simplex infection | 1.80E-02 |
Cardiac muscle contractiona | 2.40E-02 | Alzheimer’s disease | 1.10E-02 | p53 signaling pathway | 2.50E-02 |
Herpes simplex infection | 2.70E-02 | Mineral absorption | 1.30E-02 | Viral myocarditis | 2.90E-02 |
Fructose and mannose metabolisma | 3.20E-02 | Toxoplasmosis | 1.50E-02 | Legionellosis | 3.20E-02 |
Neuroactive ligand-receptor interaction | 3.20E-02 | PPAR signaling pathway | 1.90E-02 | Amyotrophic lateral sclerosis (ALS) | 3.20E-02 |
Dopaminergic synapse | 3.30E-02 | Amyotrophic lateral sclerosis (ALS) | 2.20E-02 | Sulfur metabolisma | 3.60E-02 |
Alanine, aspartate and glutamate metabolisma | 3.50E-02 | Sulfur metabolisma | 2.40E-02 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 5.00E-02 |
Glutamatergic synapse | 3.60E-02 | African trypanosomiasis | 2.50E-02 | ||
Estrogen signaling pathway | 3.70E-02 | Transcriptional misregulation in cancer | 2.90E-02 | ||
Bladder cancer | 4.10E-02 | Cardiac muscle contractiona | 3.30E-02 | ||
Dilated cardiomyopathy | 4.90E-02 | Tight junction | 4.90E-02 | ||