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Fig. 2 | BMC Genomics

Fig. 2

From: Genome-wide gene expression analysis in the placenta from fetus with trisomy 21

Fig. 2

Interaction networks of genes that are differentially expressed in T21 placentas and euploid placentas. The list of the identified genes was subjected to STRING (v. 10.0) analysis to reveal functional interactions. Each node represents a protein, and each edge represents an interaction. Thicker lines represent stronger associations. Red letters and blue letters present up-regulated genes and down-regulated genes, respectively, in the fetal placentas with T21. Green circles represent genes that are concurrently up-regulated in the adult brain, fetal brain, and fetal placenta with T21. Blue circles represent genes that were significantly associated with T21 (P < 1.46e-34)

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