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Fig. 6 | BMC Genomics

Fig. 6

From: Screening of nucleotide variations in genomic sequences encoding charged protein regions in the human genome

Fig. 6

Pattern of aa loss (a, c) and gain (b, d) in PCCs and NCCs respectively. The plots show the difference between how often an amino acid is substituted versus how often it is substituted to. The bars show the number of occurrence of substitution of each amino acid. aa: amino-acid, PCCs: Positive charge clusters, NCCs: Negative charge clusters. The plot shows that the majority of variants are rare (MAF < 0.005; p = 5 × 10 5)

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