Fig. 4

GWAS of genus Granulicatella. a Manhattan plot of the GWAS analysis in the European ancestry sample(n = 823). The red line represents the threshold of genome wide significance(p-value < 5 × 10⁻⁸). The abundance of the genus Granulicatella was transformed to z-scores in R and used as the phenotype for the European GWAS (see Methods). b Locus Zoom plot of the chromosome 7 at the most significant GWAS hit. c SNP plot for the genes IMMP2L, INHBA-AS1, and full coding gene of INHBA of the KGG analyses of the GWAS for the abundance of the genus Granulicatella