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Fig. 4 | BMC Genomics

Fig. 4

From: SAIC: an iterative clustering approach for analysis of single cell RNA-seq data

Fig. 4

Comparison of SAIC with other methods using t-SNE plots. Two dimensional t-SNE plots showing clustering of 80 lung epithelia cells into five cell groups, using (a) 216 signature genes identified by SAIC, and (b) 111 genes identified by PCA. Clusters are colored by cell class as reported in the paper published by Treutlein et al. The cells that are clustered differently from the published results are circled. The two BP cells are circled in green, and the one ciliated cell is circled in blue. The t-SNE plots of clustering results of 301 mixed single cells are shown in C and C. they are based on (c) 410 signature genes selected by SAIC and (d) 1545 variable genes selected by Seurat clustering algorithm. Color represents different cell sources correspondent to the paper published by Pollen et al. The iPS and NPC cells are circled in red

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