Fig. 4From: Genome-wide identification of key modulators of gene-gene interaction networks in breast cancer SFRP1-modulated gene interaction networks. We constructed the core interaction network modulated by a well-known prognostic gene, SFRP1, by merging the 9772 modulated interaction pairs among 1602 genes. With a connectivity of 12.2, the network was found quite intertwined. Gene pairs with significantly intensified correlation in SFRP1-on and -off samples are represented by red and green lines, respectively. Genes accounting for more than 1% of edges are labeled with gene symbols. Node size is proportional to degreeBack to article page