Table 1 Top 20 modulator genes
From: Genome-wide identification of key modulators of gene-gene interaction networks in breast cancer
Gene symbol | Num. nodes | Rank | Num. edges | Rank | Connectivity | Rank | ACI score | Rank |
|---|---|---|---|---|---|---|---|---|
KANK1 | 1727 | 36 | 9909 | 1 | 11.48 | 4 | 1.15 | 2 |
SFRP1 | 1602 | 91 | 9772 | 2 | 12.20 | 3 | 1.10 | 62 |
TMEM158 | 1878 | 9 | 8132 | 3 | 8.66 | 11 | 1.14 | 4 |
SLC16A1 | 1891 | 5 | 7276 | 6 | 7.70 | 26 | 1.18 | 1 |
POLD4 | 1940 | 3 | 7198 | 7 | 7.42 | 31 | 1.14 | 7 |
WWTR1 | 1747 | 32 | 7180 | 8 | 8.22 | 18 | 1.13 | 9 |
CYFIP2 | 959 | 888 | 7278 | 5 | 15.18 | 1 | 1.04 | 643 |
PPP1CB | 1844 | 16 | 6693 | 12 | 7.26 | 33 | 1.13 | 8 |
FAIM3 | 1342 | 384 | 7327 | 4 | 10.92 | 5 | 1.09 | 148 |
ATP5G2 | 1785 | 24 | 6218 | 20 | 6.97 | 40 | 1.14 | 3 |
ITM2A | 1775 | 28 | 6612 | 14 | 7.45 | 30 | 1.12 | 24 |
SYNM | 1557 | 120 | 6781 | 10 | 8.71 | 10 | 1.11 | 48 |
GPM6B | 1664 | 58 | 6663 | 13 | 8.01 | 22 | 1.11 | 36 |
IFRD1 | 1809 | 20 | 6107 | 23 | 6.75 | 47 | 1.14 | 5 |
LYN | 1844 | 15 | 6277 | 18 | 6.81 | 45 | 1.12 | 17 |
CRYAB | 1514 | 159 | 6940 | 9 | 9.17 | 8 | 1.09 | 120 |
GABRP | 1728 | 35 | 6184 | 22 | 7.16 | 37 | 1.13 | 13 |
LY75 | 1803 | 22 | 5988 | 25 | 6.64 | 51 | 1.13 | 12 |
SERPINB5 | 1638 | 69 | 6355 | 16 | 7.76 | 25 | 1.10 | 63 |
UBE2E3 | 1454 | 222 | 6355 | 17 | 8.74 | 9 | 1.10 | 85 |