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Fig. 12 | BMC Genomics

Fig. 12

From: Transcriptional analysis of abdominal fat in chickens divergently selected on bodyweight at two ages reveals novel mechanisms controlling adiposity: validating visceral adipose tissue as a dynamic endocrine and metabolic organ

Fig. 12

Meta-analysis of RNA-Seq analysis of abdominal fat in 7 wk.-old cockerels, which were genetically selected for a large divergence in either growth rate (HG vs. LG) or abdominal fatness (FL vs. LL), revealed a common network of highly expressed fibrinogenic genes in the leaner lines (LG and LL). This common gene interaction network was identified by IPA from a commonly-shared set of 97 DE genes identified by an independent analysis of visceral fat transcriptomes in HG vs. LG (Panel a) and FL vs. LL cockerels (Panel b) at 7 wk. The two datasets from RNA-Seq analysis of abdominal fat in the high-growth (HG) versus low-growth (LG) chickens (NCBI GEO Series Accession # GSE49121) and the fat line (FL) versus lean line (LL) broiler chickens (# GSE42980) were downloaded and independently analyzed by the USDA-funded Animal Systems Analysis and Modeling Center (ASBAMC) [48] under an approved project to LAC

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