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Table 4 Differential gene expression in abdominal fat of HG and LG chickens across three analytical methods

From: Transcriptional analysis of abdominal fat in chickens divergently selected on bodyweight at two ages reveals novel mechanisms controlling adiposity: validating visceral adipose tissue as a dynamic endocrine and metabolic organ

 

qRT-PCR Analysis

RNA-Seq Analysis

Microarray Analysis

Gene Symbol

Fold-change

P-Value

Fold-change

P-Value

Fold-change

P-Value

ALB

−345.12

1.38E-10

−169.4

5.00E-05

−1.48

0.0100

ALDOB

2.75

0.0037

−98.8

5.00E-05

1.4

0.0004

A2M

−2.27

0.0412

−52.7

5.00E-05

−5.81

0.0009

AGTR1

−2.08

0.0035

−1.93

6.63E-04

−1.92

0.0579

ANXA1

3.4

0.0002

2.29

5.00E-05

2.52

0.1303

CEBPA

1.73

0.0302

1.44

0.0008

3.19

0.0055

F5

−3.21

0.016

−3.24

6.63E-04

−4.34

0.1336

EX-FABP

−41.12

1.22E-08

−33.07

6.63E-04

−5.78

0.0069

FADS2

4.9

0.0003

4.08

5.00E-05

2.15

0.0004

FASN

2.78

0.0033

2.02

5.00E-05

1.35

0.0003

FGA

−1929.39

8.46E-11

−282.08

5.00E-05

−7.91

0.0002

HPGDS

−2.76

0.0003

−4.57

5.00E-05

−4.05

0.0033

HSD17B7

3.38

2.21E-05

3.48

5.00E-05

5.15

0.0401

LDHA

−2.74

0.015

−2.02

5.00E-05

−1.58

0.0484

LPIN1

2.22

0.0278

1.47

0.0001

1.1

0.5185

LPL

3.69

0.0002

2.15

0.0032

1.54

0.0007

ND6

−1.78

0.037

−2.55

5.00E-05

−1.28

0.0309

PPARG

2.55

0.0047

1.70

5.00E-05

1.66

0.2626

PYGL

3.07

0.0068

2.14

0.0833

1.45

0.0052

PLG

−7.22

0.0652

−299.71

0.0001

−3.52

0.0493

PGRMC1

1.36

0.1159

1.7

1

2.42

0.0205

PDK4

−4.95

0.0056

−6.14

5.00E-05

−1.25

0.0002

SCD

89.12

0.002

129.4

5.00E-05

3.53

4.52E-13

THBS2

3.57

0.0012

2.97

5.00E-05

5.18

2.33E-05

TTR

−20.01

9.86E-07

−35.72

5.00E-05

−1.73

0.0229

DHCR24

6.18

0.0001

5.46

5.00E-05

-

-

ACACA

1.85

0.056

1.82

5.00E-05

-

-

ACE

1.91

0.0269

2.47

6.63E-04

-

-

AGT

−24.69

1.73E-06

−39.29

6.63E-04

-

-

APOH

−24.98

1.48E-06

−122,00

5.00E-05

-

-

CDS2

1.99

0.0729

1.81

6.63E-04

-

-

F8

−1.49

0.0589

−2.26

6.63E-04

-

-

DGKQ

4

1.08E-05

3.18

5.00E-05

-

-

DPP7

2.73

0.0003

2.69

0.0086

-

-

FGB

−32.54

1.11E-06

−324.53

5.00E-05

-

-

FGG

−118.03

0.0016

−197.44

5.00E-05

-

-

FZD9

1.54

0.0201

2.07

6.63E-04

-

-

GPD1

3.25

6.74E-06

1.92

5.00E-05

-

-

GREM1

2.02

0.0007

3.41

5.00E-05

-

-

IGFALS

2.13

0.0287

2.49

5.00E-05

-

-

KLF5

−3.09

0.0076

−2.70

5.00E-05

-

-

OSBP2

2.1

0.0561

2.07

5.00E-05

-

-

PDE1C

−1.84

0.0078

−2.04

5.00E-05

-

-

SELE

−3.28

0.0139

−7.81

5.00E-05

-

-

SELP

−2.08

0.0089

−2.74

5.00E-05

-

-

SERPINB2

−6.11

0.0035

−8.87

5.00E-05

-

-

  1. Fold-change values [(+) is higher expression in HG and (−) is higher expression in LG chickens] provided across three independent transcriptional analysis methods at 7 wk. P-value for qRT-PCR and microarray analyses were determined by a Student’s T-test on expression values at 7 wk. P-value for RNA-Seq is corrected for FDR (FDR ≤ 0.05)
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BMC Genomics

ISSN: 1471-2164

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