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Table 1 Amino acid substitutions in the polymerase genes of EIV H3N8 among different lineages/clades

From: Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution

Genes

Residue no.

Pre-divergent

Eurasian

Florida clade 1

Florida clade 2

PA

62

I

V

V

V

 

64

E

E

E

D

 

86

M

M

M

I

 

158

K

K

K

R/G/K

 

213

R

R

K

K

 

231

A

V

V

V

 

237

E

E

E

K

 

269

R

K

K

K

 

270

I

I/M

M

M

 

321

S/N

S

S

N

 

337

A

A

T

T

 

343

A

A

E

E

 

345

L

L

I

I

 

353

K

K

R

R

 

354

T/I

T/D

I

I

 

388

S

N

S

S

 

409

S

S

N/S

S

 

432

I

I

V

V

 

450

V

V/F

I/V

I

 

476

A

A

A

T

 

532

L

F

F

F

 

626

K

K

K

R

PA-X

213

G

G

S

S

PB1

114

V

V

I

I

 

119

V

V

V

M

 

154

D

D

G

G

 

198

K

R

R

R

 

221

A

A

T/A

T

 

317

M

M

I

I

 

329

Q

Q

Q

R

 

377

D

D

D

E

 

618

E

E

E

D

 

738

E

E/D

D

D

PB1-F2

4

G

G

G

E

 

18

T

T

I

I

 

21

R

R

K

R

 

41

R

R

H

H

 

79

R

R

R

Q

PB2

12

S

S

L

L

 

105

T

T

T

A

 

251

R

R/K

R/K

K

 

344

V

M

M

M

 

511

V

I

I

I

 

590

G

S

S

S

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BMC Genomics

ISSN: 1471-2164

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