Fig. 3

Top categories of biological processes and molecular functions regulated by predicted target genes of significantly DE miRNAs at 3 hpc with E. coli. a Predicted target genes of upregulated (grey bars) and downregulated (black bars) miRNAs from PMECs at 3 hpc with E. coli were significantly enriched in biological processes such as negative regulation of biosynthetic and metabolic processes, transcription, lipid storage, cell differentiation, and regeneration. b Predicted target genes of up- and downregulated miRNAs from PMECs at 3 hpc with E. coli regulate molecular functions such as cytokine receptor and transcription repressor activity, as well as binding of cytokines, chromatin, and heat shock proteins