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Fig. 2 | BMC Genomics

Fig. 2

From: Ancient human miRNAs are more likely to have broad functions and disease associations than young miRNAs

Fig. 2

Human miRNAs are younger than protein coding genes. This figure compares the age distribution of human miRNAs (purple) and genes (green). The evolutionary origins of human miRNA are significantly younger than genes (P = 2.5e–300, Mann-Whitney U test). Human miRNA are also significantly younger than the genes they target (blue). Note that PC genes were not assigned to several branches (Hominidae, Simiiformes, Boreoeutheria, and Vertebrata) due to fewer species being present in the gene dataset. The lower resolution for gene ages does not influence our conclusions, because the genes are assigned the lower bounds on their ages

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