Fig. 3

Comparison between Orthonome, MSOAR and OrthoDB for orthologue identification across syntenically supported regions and fast evolving gene families. a A comparison of orthologue capture success in a 40 Kb syntenic region between D. sechellia and D. melanogaster. Orthologous relationships are indicated by vertical lines. Black lines = orthologous pairs supported by OrthoDB, MSOAR and Orthonome; blue lines = orthologous pairs detected only by MSOAR and Orthonome; red line = orthologous pair recovered only by Orthonome. b The newly recovered orthologous pair FBgn0004554 and FBgn0170274 in Panel A is supported by high (>90%) amino acid identity. c Orthonome is able to split OrthoDB orthogroup EOG7KHP47 (dotted orange clade) consisting of P450 monooxygenases into three independent orthogroups (solid blue clade). The three D. melanogaster genes are highlighted in green and the six additional genes that were allocated to the orthogroups by Orthonome only are marked in red. OrthoDB was unable to identify orthology to these six genes