Fig. 4

Venn diagram showing the intersection of differentially expressed genes (DEG) in the contrast “luteolysis over antigestagen” compared with the contrast “mid-gestation over antigestagen”. Lists of DEG (p < 0.01, FDR < 0.1) presented in Additional files 3 and 4 were used. Three analyses are presented: with up- and down-regulated genes (regardless of log2 ratio), or with upregulated genes (log2 > 1), or with downregulated genes (log2 < −1). When full sets of genes were used (up and down regulated), 36 genes were identified in both contrasts, 1444 genes were found in “luteolysis over antigestagen” only, and 56 genes in “mid-gestation over antigestagen”. Setting the log2 ratio > 1, 4 genes commonly over-represented in both comparisons were found, and with log2 ratio < −1, 17 commonly downregulated genes were detected