Fig. 2

Differentially abundant mouse mRNAs and clustering thereof. a Venn diagram visualizes the overlap between genes showing differential abundance (FDR < 0.01; edgeR glm likelihood-ratio tests) between i) uninfected controls and different time-points post infection and ii) between different time-points and the sum of all genes reacting to infection. Controls from challenge infection were used. b Hierarchical clustering of differentially abundant mRNAs performed on Euclidean distances using complete linkage. Cluster cut-offs (dendrogram resolution) were set to identify gene-sets with profiles interpretable in relation to the parasite lifecycle and between mice of different immune competence. Clusters are represented with color on the left-hand side of rows and additional numbering is used to refer to clusters (right)