Fig. 4

Differentially abundant E. falciformis mRNAs and clustering thereof. a Venn diagram visualizes the overlap between genes showing differential abundance (FDR < 0.01; edgeR glm likelihood-ratio tests) between intracellular stages at 3 dpi, 5 dpi and 7 dpi. b Hierarchical clustering of abundance profiles for differentially abundant mRNAs performed on Euclidean distances using complete linkage. Cluster cut-offs (dendrogram resolution) were set to identify gene-sets with profiles interpretable in relation to the parasite lifecycle. Clusters are represented with color on the left-hand side of rows and additional numbering is used to refer to clusters (right)