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Table 3 Unaffected expression of neutrophil effectors during C. albicans infection

From: Dual transcriptome of the immediate neutrophil and Candida albicans interplay

Gene

Protein

Average RPKM

± SD

Rated

S100A9

S100A9

17,890

3030

++++

S100A8

S100A8

4721

837

++++

NCF2

NADPH oxidase, p67

669

103

+++

LYZ

lysozyme C

435

91

+++

S100A12

S100A12

372

78

+++

NCF4

NADPH oxidase, p40

293

40

+++

MMP9

gelatinase B

258

49

+++

RAC2

NADPH oxidase, Rac1 or Rac2

236

29

+++

CYBA

NADPH oxidase, p22-PHOX

115

19

++

NCF1

NADPH oxidase, p47

62

13

++

CAT

catalase

51

8

++

RAC1

NADPH oxidase, Rac1 or Rac2

25

5

+

CAMP

cathelicidin, LL-37

25

6

+

CYBB

NADPH oxidase, gp91-PHOX

16

3

+

HMGB1

high-mobility group protein 1/amphoterin

8

1

+

TCN1

transcobalamin-I

4

1

–

CRISP3

cysteine-rich secretory protein-3

1

0

–

LTF

lactotransferrin

1

0

–

ELANE

neutrophil elastase

0

0

–

DEFA1B

defensin 1

0

0

–

DEFA1

neutrophil defensin 1

0

0

–

MMP8

neutrophil collagenase

0

0

–

CTSG

cathepsin G

0

0

–

MPO

myeloperoxidase

0

0

–

PRTN3

proteinase 3

0

0

–

BPI

bactericidal/permeability-increasing protein

0

0

–

DEFA3

neutrophil defensin 3

0

0

–

DEFA4

neutrophil defensin 4

0

0

–

DEFA5

defensin 5

0

0

–

DEFA6

defensin 6

0

0

–

  1. The transcript levels of typical neutrophil antimicrobial effector genes that were not differentially expressed during cocultivation with C. albicans was determined over all time points and conditions. Average and SD RPKM values are displayed and rated to illustrate the expression level. ++++: RPKM >1000; +++: RPKM ≥200; ++: RPKM ≥30; +: RPKM ≥5; −: RPKM ≥0