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Table 4 Transcription profile of selected C. albicans effectors genes upon neutrophil challenge

From: Dual transcriptome of the immediate neutrophil and Candida albicans interplay

  C. albicans yeast [log2] C. albicans hyphae [log2]
15 min 30 min 60 min NETs 15 min 30 min 60 min NETs
SOD1 −0.38 −0.02 −1.39 −0.41 1.15 0.72 0.24 0.94
SOD2 −0.60 −0.61 −0.62 0.12 −0.40 −0.66 −0.48 0.63
SOD3 1.75 −0.68 2.98 0.55 −0.24 0.30 1.19 1.04
SOD4 1.18 2.24 2.53 0.57 0.65 1.26 1.49 0.31
SOD5 1.45 0.90 0.43 1.64 0.91 0.83 0.56 0.15
SOD6 1.45 0.90 0.43 1.64 0.84 0.42 0.41 1.31
CAT1 0.67 −0.08 −1.08 1.33 1.00 −0.04 −0.87 1.20
TRX1 0.45 0.06 −0.97 0.56 1.19 0.61 0.28 0.83
ECE1 3.81 6.63 9.22 1.15 −1.16 −1.06 −1.48 −0.22
PRA1 3.32 1.03 1.49 1.77 −0.27 0.35 0.63 0.90
ALS3 1.56 3.05 4.52 −0.37 −1.13 −1.25 −1.62 −0.52
  Neutrophils   Neutrophils  
  1. The transcript pattern of typical C. albicans effector genes affected during neutrophil encounter and NETs challenge is displayed by fold change. The transcript levels during neutrophil infection were corrected by the transcript levels in the same environment without neutrophils (medium, temperature) at every given time point