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Table 8 GO Biological processes associated with the novel hub genes

From: Biological networks in Parkinson’s disease: an insight into the epigenetic mechanisms associated with this disease

Novel hub genes

GO Biological Process

GO Terms

MAGED1

Regulation of transcription, DNA-templated

GO:0006355

Regulation of transcription from RNA polymerase

GO:0006357

II promoter

 

Circadian regulation of gene expression

GO:0032922

Regulation of circadian rhythm

GO:0042752

Regulation of apoptotic process

GO:0042981

Positive regulation of apoptotic process

GO:0043065

Positive Regulation of MAP kinase activity

GO:0043406

Negative regulation of transcription, DNA-templated

GO:0045892

GO:0045893

Positive regulation of transcription, DNA-templated

Neurotrophin TRK receptor signaling pathway

 

AP3B2

Intracellular protein transport

GO:0006886

Post-Golgi vesicle-mediated transport

GO:0006892

Anterograde axon cargo transport

GO:0008089

Anterograde synaptic vesicle transport

GO:0048490

STXBP1

platelet degranulation

GO:0002576

energy reserve metabolic process

GO:0006112

vesicle docking involved in exocytosis

GO:0006904

synaptic transmission

GO:0007268

neurotransmitter secretion

GO:0007269

neuromuscular synaptic transmission

GO:0007274

axon target recognition

GO:0007412

regulation of synaptic vesicle priming

GO:0010807

glutamate secretion

GO:0014047

protein transport

GO:0015031

AF1Q

Positive regulation of apoptotic process

GO:0043065

Positive regulation of transcription, DNA-templated

GO:0045893

Positive regulation of mitochondrial depolarization

GO:0051901

Positive regulation of release of cytochrome c from mitochondria

GO:0090200

Extrinsic apoptotic signaling pathway

GO:0097191

Intrinsic apoptotic signaling pathway

GO:0097193

GASP

Endosome to lysosome transport

GO:0008333

G-protein coupled receptor catabolic process

GO:1,990,172

G-protein coupled receptor catabolic process

GO:1,990,172

C14ORF78

Plasma membrane repair

GO:0001778

MAN1C1

Protein N-linked glycosylation

GO:0006487

Protein N-linked glycosylation via asparagine

GO:0018279

Post-translational protein modification

GO:0043687

Cellular protein metabolic process

GO:0044267

HNRPC

mRNA splicing, via spliceosome

GO:0000398

Osteoblast differentiation

GO:0001649

RNA splicing

GO:0008380

Gene expression

GO:0010467

ATP-dependent chromatin remodeling

GO:0043044

3′-UTR-mediated mRNA stabilization

GO:0070935