Table 3 The top ten most overrepresented Biological Functions in each species, determined using g:Cocoa
From: Patterns of host gene expression associated with harboring a foregut microbial community
Function | GO Term | No. genes in term | No. genes overexpressed in woodrats | No. genes overexpressed in lab rats |
|---|---|---|---|---|
Overrepresented in woodrats | ||||
 Cellular component organization | GO:0016043 | 5139 | 347 | 252 |
 Metabolic process | GO:0008152 | 11,355 | 638 | 580 |
 Actin cytoskeleton organization | GO:0030036 | 520 | 65 | 18 |
 Intracellular signal transduction | GO:0035556 | 2241 | 176 | 1 |
 Cellular component morphogenesis | GO:0032989 | 1204 | 112 | 29 |
 Regulation of multicellular organismal process | GO:0051239 | 2423 | 175 | 62 |
 Regulation of molecular function | GO:0065009 | 2460 | 174 | 61 |
 Regulation of intracellular signal transduction | GO:1,902,531 | 1417 | 107 | 1 |
 Cell migration | GO:0016477 | 1081 | 53 | 55 |
 Muscle contraction | GO:0006936 | 240 | 25 | 3 |
Overrepresented in lab rats | ||||
 Single-organism metabolic process | GO:0044710 | 4526 | 265 | 305 |
 Immune response | GO:0006955 | 1107 | 10 | 69 |
 Defense response | GO:0006952 | 1264 | 20 | 65 |
 Organic hydroxy compound metabolic process | GO:1,901,615 | 431 | 22 | 43 |
 Positive regulation of cell activation | GO:0050867 | 250 | 8 | 21 |
 Positive regulation of T cell activation | GO:0050870 | 155 | 5 | 16 |
 Neutrophil migration | GO:1,990,266 | 94 | 1 | 11 |
 Nuclear DNA replication | GO:0033260 | 15 | 1 | 6 |
 L-serine biosynthetic process | GO:0006564 | 4 | 0 | 4 |
 Localization | GO:0051179 | 5203 | 289 | 305 |