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Fig. 8 | BMC Genomics

Fig. 8

From: Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma

Fig. 8

Gene (a) and protein expression (b) of TNFRSF12A, PTCH1, CDC25A and IL8 in bronchial biopsies from horses with and without asthma. TNFRSF12A, CDC25A and IL8 mRNA, expressed as counts per million (CPM), was up-regulated in asthmatic and down-regulated in non-asthmatics following challenge, while PTCH1 was slightly down-regulated in asthmatics and up-regulated in non-asthmatics. (b) IHC results approximated gene expression with a relative increase in TNFRSF12A, CDC25A and IL8 immunoreactivity and decrease in PTCH1 immunoreactivity in asthmatic animals

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