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Table 1 Overview of the datasets identified for analysis

From: Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets

Dataset ID Platform Species Sample Number of samples Reference
E-MTAB-463 and E-MTAB-465 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F Homo sapiens β-cells and α-cells β-cells: 4
α-cells: 4
Dorrell et al., 2014
RNA-seq Homo sapiens Sorted β-cells, α-cells and exocrine cells (duct and acinar) β-cells: 3
α-cells: 3
Exocrine cells: 2
Bramswig et al., 2013
EGAS00001000442 RNA-seq Homo sapiens Sorted β-cells, α-cells and non-β-cells 7 DNA libraries, pooled Nica et al., 2013
GSE30803 [HG-U133A] Affymetrix Human Genome U133A Array Homo sapiens Islets (and 16 other primary cell types) Islets: 3 Martens et al., 2011
RNA-seq Mus musculus β-cells and islets Unknown. Data for 5 additional cell types downloaded from NCBI Ku et al., 2012
GSE13381 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array Rattus norvegicus β-cells and α-cells β-cells: 2
Non-β-cells: 2
Kutlu et al., 2009
GSE10785 Rosetta/Merck Mouse 44 k 1.0 microarray Mus musculus Islets (and 5 other primary cell types) Islets: 40 Keller et al., 2008
GSE35296 RNA-seq Homo sapiens Islets Control: 5
IL-1β and IFN-γ: 5
Eizirik et al., 2012
[HG-U133A] Affymetrix Human Genome U133A Array Homo sapiens Islets Control: 3
IL-1β and IFN-γ: 3
Ylipaasto et al., 2005
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array Rattus norvegicus FACS purified β-cells For control and cytokine stimulation at each time point: 3 Ortis et al., 2010
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array Rattus norvegicus INS-1E rat insulinoma cell line For control and cytokine stimulation at each time point: 3 Moore et al., 2011
GSE40642 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array Rattus norvegicus INS-1ab rat insulinoma cell line Control: 8
IL-1β: 20
PDX-1 overexpression: 8
PDX-1 overexpression and IL-1β: 20
Hansen et al., 2012
GSE49786 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array Rattus norvegicus Islets Untreated: 5
Pdx-1 overexpression: 5
Hayes et al., 2013
E-MTAB-127 A-CBIL-10-UPenn Mouse PancChip 6.1 Mus musculus Islets and MIN6 murine insulinoma cell line Islets Pdx-1+/−: 3
Islets Pdx-1+/+: 3
MIN6 treated: 4
MIN6 control: 4
Sachdeva et al., 2009
GSE12817 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array Rattus norvegicus Islets 2 mM Glucose: 4
5 mM Glucose: 4
10 mM Glucose: 4
30 mM Glucose: 4
Bensellam et al., 2009
GSE25724 [HG-U133A] Affymetrix Human Genome U133A Array Homo sapiens Islets Non-diabetic: 7
Diabetic: 6
Dominguez et al., 2011
GSE20966 [U133_X3P] Affymetrix Human X3P Array Homo sapiens β-cell-enriched pancreatic tissue Non-diabetic: 10
Diabetic: 10
Marselli et al., 2010
GSE38642 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] Homo sapiens Islets Non-diabetic: 54
Diabetic: 9
Taneera et al., 2012