Table 3 Significant associated genes identified by RareProb-C comparing to the ones highlighted in the integrated germline-somatic research on the same dataset
Gene name | RareProb-C | OV research |
|---|---|---|
BRCA1 | 3.0×10−14 | 2.0×10−8 |
BRCA2 | 4.5×10−15 | 8.9×10−6 |
CHEK2 | 2.4×10−15 | 0.11∗ |
BRIP1 | 5.2×10−10 | 0.11∗ |
USP6 | 3.3×10−12 | Not Significant ∗ |
PALB2 | 5.2×10−10 | Not Significant ∗ |
ATM | 2.9×10−9 | Not Significant |
PCSK7 | 7.6×10−8 | Not Significant |
FLT3 | 5.8×10−7 | Not Significant |