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Fig. 5 | BMC Genomics

Fig. 5

From: XCAVATOR: accurate detection and genotyping of copy number variants from second and third generation whole-genome sequencing experiments

Fig. 5

XCAVATOR results on the TGS PacBio data. Panel a shows the histograms of DOC data fromf the PacBio WGS experiments for different sequencing coverages with the superimposed Poisson (dashed lines) and negative binomial (solid lines) distributions. The distance between RC and Poisson (DP) and negative binomial (DNB) distributions are calculated with the Kolmogorov-Smirnov statistic D. Panels b and d report the correlation between DOC data and GC content % and mappability. Panels c and e show the effect of median normalization approach on GC content % and mappability. The violin plots of panel f show the correlation between absolute number of DNA copies obtained by DOC signals and those previously estimated by McCarroll et al. Panels g and h summarize the TPR and number of FP detected by XCAVATOR with PacBio and Illumina data

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BMC Genomics

ISSN: 1471-2164

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