Fig. 5
Heat map image of differentially transcribed genes involved in OXPHOS. Three groups of fish were fed 23 days at a daily ration of 25 g/kg body weight with diets HLL, MHL or LLH. A fourth group of animals was fasted for the same period. Hierarchical clustering of differentially expressed genes in the liver a and the skeletal muscle b is represented from microarray data obtained from tissue samples of S. aurata fed with diets HLL, MHL or LLH versus starved fish) with an adjusted P value <0.05 and a difference of at least 2-fold in the normalised intensity ratio (Cy5/Cy3 or Cy3/Cy5) for one or more dietary conditions. Results are presented as logFC mean value (n = 4 fish); logFC is the log2 transformed fold change. Green colour denotes downregulated genes and red colour upregulated genes in fed animals. ATP synthase subunit alpha (ATP5A1), ATP synthase F(0) complex subunit C3 (ATP5G3), ATP synthase subunit e isoform 1 (ATP5I1), ATPase inhibitor (ATPIF1), coenzyme Q-binding protein COQ10 (COQ10), cytochrome c oxidase subunit 4 isoform 2 (COX4I2), cytochrome c oxidase subunit 5A isoform 2 (COX5A2), cytochrome c oxidase subunit 6A2 (COX6A2), cytochrome c oxidase subunit 7A2 (COX7A2), cytochrome c oxidase subunit 5B isoform 1 (COX5B1), cytochrome c oxidase subunit 6B1 (COX6B1), cytochrome c oxidase subunit 6B isoform 1B (COX6B1B), cytochrome c oxidase subunit 8B (COX8B), mitochondrial inner membrane protein COX18 (COX18), cytochrome c (CYCS), electron transfer flavoprotein subunit beta (ETFB), NADH-ubiquinone oxidoreductase chain 1 (MT-ND1), NADH-ubiquinone oxidoreductase chain 2 (MT-ND2), NADH-ubiquinone oxidoreductase chain 4 (MT-ND4), NADH-ubiquinone oxidoreductase chain 5 (MT-ND5), NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 (NDUFA4), NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2), NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10 (NDUFA10), NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (NDUFA11), NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 (NDUFAF3), protein SCO1 homolog (SCO1), succinate dehydrogenase assembly factor 4 (SDHAF4), ADP/ATP translocase 1 (SLC25A4), ADP/ATP translocase 2 (SLC25A5), ADP/ATP translocase 3 (SLC25A6), ubiquinol-cytochrome-c reductase complex assembly factor 1 (UQCC1), cytochrome b-c1 complex subunit 10 isoform A (UQCR11A), cytochrome b-c1 complex subunit 1 (UQCRC1), cytochrome b-c1 complex subunit 2 (UQCRC2), cytochrome b-c1 complex subunit 6 (UQCRH)