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Table 5 Methylation motifs and the responsible methylases identified in P. freudenreichii

From: De novo assembly of genomes from long sequence reads reveals uncharted territories of Propionibacterium freudenreichii

  1. Recognition sequences in parentheses indicates the methylase responsible cannot be assigned unambiguously. Modified bases are marked in colour; “not annotated” indicates there is no locus tag as the gene is not annotated in the GenBank file. Color coding for the methylation types Blue: 6 mA; Orange: 4mC; Purple: 5mC
  2. *It is possible that it is really M.PfrJS17ORF2252P that is the active methylase in this organism. M.PfrJS17ORF2252P shares 99% aa sequence identity with M.PfrJS22I, but its corresponding S protein is truncated
  3. **It is possible that it is really M.PfrJS22ORF850P that is the active methylase in this organism. M.PfrJS22ORF850P is 100% identical to M.PfrJS17I, as are their corresponding S proteins while the R proteins differ by one amino acid (475 Ala:Gly)