Fig. 3

SaVanT Distinguishes Between Patients, Cell Types, and Underlying Biology. a SaVanT output for expression data from acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) patients. ‘Signature value’ refers to the average of gene expression values in a signature. Z-scores (across the entire signature value matrix) are shown for both heatmaps. b SaVanT output for expression data from 99 patients with acute infections (either Influenza A or bacterial pneumonia). The infection type for each patient is represented by a hatched circle (Influenza A) or filled triangle (bacterial pneumonia). The numbers below each cluster quantify the proportion of infection types. The difference between the signature values and the average signature value per signature is shown. c SaVanT output for expression data from different skin diseases