Genomic regions associated with host response to porcine reproductive and respiratory syndrome vaccination and co-infection in nursery pigs

Table 6 QTL Test results for the main/interaction effects of SNPs associated with PRRS and PCV2b VL

Trait	Effect^a	SNP List^b	# of SNPs above threshold	# of health QTL in region^c	Total # of QTL in region^d	P-value
PRRS VL	Main	2	528	189	1046	0.33
		2.5	168	64	382	0.67
		3	37	34	83	4.6E-7
	Interaction	2	516	246	1239	0.02
		2.5	159	79	442	0.44
		3	42	2	97	0.99
PCV2b VL	Main	2	823	372	1943	0.03
		2.5	350	260	1076	2.3E-8
		3	160	162	609	1.5E-8
	Interaction	2	520	182	1140	0.92
		2.5	156	42	399	0.99
		3	44	9	126	0.99

^aEffect: The effect of SNP across groups vaccinated, or not, for PRRS (main) or the effect of SNP interacting with PRRS vaccination status (interaction)
^bSNP List: Lists of SNPs from the GWAS with a –log₁₀ p-value above 2, 2.5 or 3
^cThe total number of health QTL in the genome (after filtering) is 1732
^dThe total number of QTL in the genome (i.e. across all QTL types and after filtering) is 9892

ISSN: 1471-2164