From: Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE
FDNC5 (rs16835198)
Genotype
FOXO3A Presence of rs2802292 T-allele
P-value
OR (95% CI)
Controls (n = 754)
Centenarians (n = 668)
GG
147 (19.5%)
162 (24.3%)
0.035
1.32 (1.03–1.70)
GT
378 (50.1%)
323 (48.3%)
NS
–
TT
229 (30.4%)
183 (27.4%)