Table 3 The top 10 up- and down-regulated genes of 120 d vs 240 d Laiwu pigs
Regulate | Gene | FPKM (120 d) | FPKM (240 d) | Log2(FC)a | Function |
|---|---|---|---|---|---|
Up | CHRNG | 0.23 | 7.45 | 5.04 | GO:0006936: muscle contraction |
CYP1A1 | 0.15 | 2.43 | 4.07 | GO:0008395: steroid hydroxylase activity | |
ISG15 | 4.48 | 65.3 | 3.86 | KEGG Pathway: RIG-like receptor signalling pathway | |
DNAJB1 | 14.66 | 197.69 | 3.75 | GO:0001671: ATPase activator activity | |
NREP | 21.21 | 240.52 | 3.5 | GO:0017015: Regulation of transforming growth factor beta receptor signaling pathway | |
EGR1 | 11.7 | 111.05 | 3.25 | GO:0006366: Transcription from RNA polymerase II promoter | |
G0S2 | 5.16 | 47.34 | 3.2 | Reactome Pathway: Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha | |
TNNT2 | 8.55 | 70.02 | 3.03 | Reactome Pathway: Striated muscle contraction | |
ATP5J2 | 1 | 8.01 | 3.02 | GO:0006754: ATP biosynthetic process | |
FAM213B | 87.24 | 616.05 | 2.82 | KEGG Pathway: Arachidonic acid metabolism | |
Down | A2M | 11.94 | 0.18 | −6.08 | GO:0004867: serine-type endopeptidase inhibitor activity |
CDH2 | 38.08 | 3.01 | −3.66 | GO:0008013: beta-catenin binding | |
NOS1 | 7.36 | 0.7 | −3.4 | GO:0006809: nitric oxide biosynthetic process | |
ZIC3 | 1.32 | 0.13 | −3.35 | GO:0007368: determination of left/right symmetry | |
PDK4 | 722.31 | 96.27 | −2.91 | GO:0004672: protein kinase activity | |
FBXO32 | 53.3 | 7.7 | −2.79 | KEGG Pathway: FoxO signalling pathway | |
KLF11 | 7.56 | 1.18 | −2.68 | GO:0044212: transcription regulatory region DNA binding | |
DIAPH1 | 89.73 | 18.76 | −2.26 | GO:0005815: microtubule organizing centre | |
UCP3 | 111.83 | 23.33 | −2.26 | GO:0017077: oxidative phosphorylation uncoupler activity | |
SORBS1 | 73.38 | 16.07 | −2.19 | KEGG Pathway: PPAR signalling pathway |