Skip to main content

Table 2 Functional annotation for 12 genes differentially regulated throughout all phases of wound response

From: Transcriptomic responses to wounding: meta-analysis of gene expression microarray data

Term

Number of genes

p-value

Genes

GO:0022617~extracellular matrix disassembly

4

1.43E-05

CD44, MMP12, SPP1, TIMP1

GO:0005615~extracellular space

7

5.39E-05

ICAM1, CCL2, LGALS3, ANXA1, SPP1, ANXA2, TIMP1

GO:0008360~regulation of cell shape

4

8.91E-05

ICAM1, CCL2, PDPN, ANXA1

GO:0009986~cell surface

3

2.16E-04

CCL2, LGALS3, ANXA1

GO:0002548~monocyte chemotaxis

3

3.31E-04

ICAM1, CCL2, CD44

GO:0070374~positive regulation of ERK1 and ERK2 cascade

3

5.58E-03

ICAM1, CD44, SPP1

GO:0030198~extracellular matrix organization

5

6.96E-03

ICAM1, PTPRC, CD44, ANXA1, ANXA2

GO:0048246~macrophage chemotaxis

2

8.49E-03

CCL2, LGALS3

GO:0006954~inflammatory response

3

2.44E-02

CCL2, ANXA1, SPP1

GO:0043434~response to peptide hormone

2

2.85E-02

ANXA1, TIMP1

GO:0043066~negative regulation of apoptotic process

3

3.43E-02

CD44, ANXA1, TIMP1

GO:0030593~neutrophil chemotaxis

2

4.24E-02

CCL2, LGALS3

  1. The p-values for the terms significant after Benjamini correction (p-value adjusted <0.05) are distinguished with bold font
  2. The 12 genes differentially regulated during all wound healing phases are listed in Fig. 7