Fig. 2

a-d Accuracy of imputation relying on the coalescent (black) and with IMPUTE2 (gray) represented by mean concordance rates with the corresponding 95% confidence intervals (shown as error bars). a 1000 haplotypes were simulated under the basic coalescent. Genotypes were imputed based on the basic coalescent and with IMPUTE2 without recombination. Results are presented for all variants and stratified by minor allele frequency. b Different total numbers of haplotypes were simulated under the basic coalescent. Genotypes were imputed based on the basic coalescent and with IMPUTE2 without recombination. c Haplotypes were simulated under the basic coalescent extended to accommodate different exponential growth rates (α). Genotypes were imputed based on the coalescent with growth, and with IMPUTE2 without recombination. d Haplotypes were simulated under the coalescent extended to consider different numbers of subpopulations (β). Genotypes were imputed based on the coalescent with population structure and with IMPUTE2 without recombination