Skip to main content

Table 3 Comparison between CRISPOR, Cas-OFFinder and the proposed algorithm on off-target homology search for EMX1 sgRNA guide sequence

From: Whole genome analysis of CRISPR Cas9 sgRNA off-target homologies via an efficient computational algorithm

  Number of off-target homologies identified
Number of base mismatches 0 1 2 3 4
CRISPOR 0 0 6 38 296
Cas-OFFinder 0 0 1 18 273
Our Algorithm (with Secondary PAM) 0 0 6 87 1227
Our Algorithm (without secondary PAM) 0 0 1 18 273