Fig. 4
Bubble plots showing enriched GO terms generated from sex-biased genes. “Z-score” was calculated for each term using the formula: male-biased minus female-biased gene number divided by the square root of sex-biased gene number. The significant GOs are indicated above the yellow line. The bubbles calculated with minus z-scores represent GOs containing more female-biased genes, while GOs with more male-biased genes have z-scores larger than zero. The bubble size represents the number of genes. The GO descriptions on the right are listed from the highest to lowest significance of enrichment. (a) Level one terms; (b) after removing all parental terms