Fig. 3
From: Mosaic autosomal aneuploidies are detectable from single-cell RNAseq data
Allele-specific expression datasets support the method’s aneuploidy calls. a Chromosomes with higher-confidence aneuploidy calls show greater allele-specific expression (ASE) deviation than cells that are not called (p<10−9, Mann-Whitney U test). The ASE deviation was corrected for systematic ASE differences for each embryo and for each autosome (Methods). Z-scores to the right of the dashed line are significant after FDR-correction. Values above Z-score bins are the number of chromosomes in each bin. b Trisomic and monosomic chromosomes show greater ASE deviation than chromosomes with normal-ploidy (p<10−8 and p<10−2, respectively; Mann-Whitney U test). Black circles indicate the mean deviation. Violin plots are area normalised. Values above the plots are the number of chromosomes considered