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Table 2 Relatedness of clinical and water MLVA genotypes of Vibrio cholerae by outbreak

From: Genetic relatedness of Vibrio cholerae isolates within and between households during outbreaks in Dhaka, Bangladesh

 

All Outbreaks

Cholera Outbreaks

p-value†

Outbreak 1

Outbreak 2

Outbreak 3

June to

August 2013

September 2013 to

January 2014

March to

June 2014

Samples with at least two isolates with different MLVA genotypes

 Clinical Samples

76% (42/55)

47% (8/17)

79% (15/19)

100% (19/19)

<0.0001

 Water Samples

100% (46/46)

100% (8/8)

100% (15/15)

100% (23/23)

‡

Isolates with unamplified VCA0171 Allele

 Clinical Isolates

0% (0/288)

0% (0/139)

0% (0/109)

0% (0/40)

‡

 Water Isolates

30% (99/333)

66% (52/79)

39% (46/118)

1% (1/136)

<0.0001

Household Characteristics

 Household member and water isolates with identical MLVA genotypes

58% (18/31)

50% (3/6)

55% (6/11)

64% (9/14)

0.09

 Index cholera patient and source water isolate with identical MLVA genotypes

56% (15/27)

40%(2/5)

56% (5/9)

62% (8/13)

0.09

 Household member and source water isolates with identical MLVA genotypes

52% (16/31)

50% (3/6)

46% (5/11)

57% (8/14)

0.09

 Household member and stored water isolates with identical MLVA genotypes

40% (2/5)

0% (0/1)

50% (1/2)

50% (1/2)

0.4

 Household member isolates with identical MLVA genotypes

82% (9/11)

66% (2/3)

75% (3/4)

100% (4/4)

0.2

  1. †Fisher Exact Test
  2. ‡ Fisher exact couldn’t be calculated because all proportions were the same across outbreaks