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Table 3 Summary of genotyping results from three molecular markers analysed in 37 field samples

From: Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections

Marker He Mean MOI Number SNPsa Number Haplotypes Concordance of MOI
Κ
msp2 CE 0.948 2.19 NA 25 Reference
cpmp 0.957 2.41 45 27 0.71b (good)
csp 0.574 1.54 10c 4 0.38d (poor)
  1. a With respect to the reference sequence of P. falciparum strain 3D7
  2. b Cohen’s Kappa (2 raters, weights = equal): z = 6.64, p-value = 3.04e-11
  3. c 4/10 SNPs are fixed within these 37 field samples
  4. d Cohen’s Kappa (2 raters, weights = equal): z = 4.48, p-value = 7.61e-6
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BMC Genomics

ISSN: 1471-2164

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