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Table 3 Summary of genotyping results from three molecular markers analysed in 37 field samples

From: Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections

Marker

He

Mean MOI

Number SNPsa

Number Haplotypes

Concordance of MOI

Κ

msp2 CE

0.948

2.19

NA

25

Reference

cpmp

0.957

2.41

45

27

0.71b (good)

csp

0.574

1.54

10c

4

0.38d (poor)

  1. a With respect to the reference sequence of P. falciparum strain 3D7
  2. b Cohen’s Kappa (2 raters, weights = equal): z = 6.64, p-value = 3.04e-11
  3. c 4/10 SNPs are fixed within these 37 field samples
  4. d Cohen’s Kappa (2 raters, weights = equal): z = 4.48, p-value = 7.61e-6