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Table 3 Enriched genetic pathways between Restricted Anovulatory and Control groups from Innatedb

From: Effect of short term diet restriction on gene expression in the bovine hypothalamus using next generation RNA sequencing technology

Pathway name Genes Total no. of genes in pathway P value
RIG-I-like receptor signaling pathway CXCL10 ↑, Q1KLR3 ↑, IFIH1 ↑, IL8 70 0.000815541
Activation of NMDA receptor upon glutamate binding and postsynaptic events ADCY1 ↓, GRIN2A ↓, GRIN2C 32 0.002998833
Post NMDA receptor activation events ADCY1 ↓, GRIN2A ↓, GRIN2C 32 0.002998833
Long-term potentiation ADCY1 ↓, GRIN2A ↓, GRIN2C ↓, ITPR1 68 0.003241851
Cytosolic DNA-sensing pathway CXL10 ↑, Q1KLR3 ↑, ZBP1 55 0.003482075
Transmission across Chemical Synapses ADCY1 ↓, GRIN2A ↓, GRIN2C ↓, SLC6A3 76 0.00456686
Synaptic Transmission ADCY1 ↓, GRIN2A ↓, GRIN2C ↓, SLC6A3 81 0.005631178
Gata3 participate in activating the th2 cytokine genes expression ADCY1 ↓, IL1A 18 0.007137619
D-Arginine and D-ornithine metabolism DAO 1 0.007150141
Neuroactive ligand-receptor interaction CALRL ↑, A6QQP6 ↑, GRIK3 ↓, GRIN2A ↓, GRIN2C ↓, TRY2 301 0.009258012
Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell ADCY1 ↓, GRIN2A ↓, GRIN2C 48 0.009603978
Unblocking of NMDA receptor, glutamate binding and activation GRIN2A ↓, GRIN2C 12 0.009663882
  1. Expression is Restricted Anovulatory relative to Control. eg. CXL10 ↑ means RA has increased expression compared to C