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Fig. 3 | BMC Genomics

Fig. 3

From: Independent impacts of aging on mitochondrial DNA quantity and quality in humans

Fig. 3

Distribution of mtDNA copy number in the UK10K Twins cohort and its association with age. a mtDNA copy number was estimated using WGS data by comparing the mean sequencing coverage of mtDNA and nDNA. The distribution of mtDNA copy number was positively skewed, and most individuals had moderate numbers of mtDNA (mean 169 and median 188). b mtDNA copy number was negatively correlated with age (β = −0.395, P = 0.00972). Blue line represents the linear regression line. For every 10 years, mtDNA copy number decreases about 4 copies

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