Fig. 4
From: Independent impacts of aging on mitochondrial DNA quantity and quality in humans
Association between mtDNA heteroplasmy number and copy number. mtDNA copy number was significantly associated with the total heteroplasmy number within an individual, adjusting for age and mean nuclear sequencing coverage (β = −4.34, P = 0.007). Individuals harboring higher numbers of heteroplasmies were more likely to have low mtDNA copy number