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Table 1 Heteroplasmy number in different age groups

From: Independent impacts of aging on mitochondrial DNA quantity and quality in humans

Age Group

< 40

40–50

50–60

60–70

> 70

Age Mean

30.12

45.24

55.27

64.28

74.07

Age SD

6.41

2.72

2.92

2.94

3.35

Individual count

166

267

464

447

167

Heteroplasmy counta

0.70; (44.6%)

0.72; (47.2%)

0.89; (55.0%)

0.98; (53.5%)

1.11; (60.0%)

Heteroplasmy count (MAF 2–5%)

0.41; (28.3%)

0.48; (32.2%)

0.56; (36.9%)

0.62; (38.7%)

0.68; (39.5%)

Heteroplasmy count (MAF > 5%)

0.29; (22.9%)

0.24; (20.6%)

0.33; (28.4%)

0.37;(27.7%)

0.43; (32.3%)

  1. anumbers in parentheses indicate the proportion of individuals harboring heteroplasmy with specified MAF cutoffs. An individual can have heteroplasmies in both MAF groups