Fig. 6

Comparative HPLC analysis between S. clavuligerus ATCC 27064 and S. clavuligerus pSCL4− . a Components determined in S. clavuligerus ATCC 27064 extracts (upper pannel) and S. clavuligerus pSCL4− extract (lower panel). 1:MOPS; 2: demethylenenocardamine and deoxynocardamine; 3: Nocardamine; 4: 8-amino-2-methyl-7-oxononanoic acid, 5: 2-hexyl-5-methyl-1,3-benzenediol (resorcinol) and 2-butyl-5-propyl-resorcinol, 6: 2-hexyl-5-methyl-1,3-benzenediol and 2-butyl-5-propyl-resorcinol, 1: MOPS, 7:citiolone, 8: N-propanoyl-3-aminodihydro-2(3H)-thiophenone (N-propionyl-homocysteine thiolactone); 9:holomycin, 10:nocardamine, 11: N-propionylholothin. b Chemical structure of the above indicated compounds