Skip to main content

Advertisement

Table 2 Genes encoding regulatory proteinsa which are up- or down-regulated in S. clavuligerus pSCL4-

From: Discovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid

Gene Product Mc BH-corrected P-value Fold change
22.5 h 46.5 h 60 h 22.5 h 46.5 h 60 h 22.5 h 46.5 h 60 h
Up-regulated
 SCLAV_2377 ECF-subfamily RNA polymerase sigma factor 2.42 1.91 1.76 1.80E-05 1.43E-04 2.61E-04 5.36 3.77 3.39
 SCLAV_2378 Lipoprotein cseA 1.30 0.83 1.23 1.55E-05 1.08E-03 8.98E-06 2.46 1.77 2.35
 SCLAV_2379 Transcriptional regulatory protein cseB 1.34 1.08 1.71 1.35E-03 6.52E-03 5.56E-05 2.54 2.11 3.26
 SCLAV_2380 Sensor protein 1.60 1.22 2.19 6.07E-04 5.17E-03 9.20E-06 3.04 2.33 4.56
 SCLAV_3934 Alkyl hydroperoxide reductase ahpD 0.61 1.24 3.66 3.34E-01 2.15E-02 2.27E-07 1.53 2.37 12.63
 SCLAV_3935 Alkyl hydroperoxide reductase 0.57 1.27 3.90 3.35E-01 1.29E-02 3.82E-08 1.49 2.41 14.89
 SCLAV_3936 Putative LysR-family transcriptional regulator 1.11 1.48 2.06 1.47E-02 1.09E-03 2.09E-05 2.16 2.79 4.17
 SCLAV_4082 RNA polymerase sigma factor RpoE 1.23 1.64 0.66 2.61E-03 1.06E-04 8.26E-02 2.35 3.11 1.58
 SCLAV_4083 Putative anti-sigma factor 1.06 1.30 0.29 4.63E-03 5.29E-04 4.56E-01 2.08 2.46 1.22
Down-regulated
 SCLAV_0691 RNA polymerase sigma factor 1.35 1.62 1.21 2.66E-03 3.19E-04 3.78E-03 2.55 3.08 2.32
 SCLAV_2573 WhiB-family transcriptional regulator 2.74 3.47 4.47 6.05E-04 3.12E-05 9.92E-07 6.68 11.11 22.16
 SCLAV_2833 Putative serine/threonine kinase anti-sigma factor 1.16 1.70 2.54 4.77E-02 2.92E-03 3.22E-05 2.24 3.24 5.81
 SCLAV_3047 Predicted transcriptional regulator 1.43 2.74 2.45 2.53E-02 5.41E-05 1.40E-04 2.69 6.70 5.47
 SCLAV_3146 TetR-family transcriptional regulator 1.04 1.20 1.55 5.19E-03 1.16E-03 5.07E-05 2.06 2.29 2.93
 SCLAV_3422 Transcriptional regulator 1.80 2.65 3.79 3.07E-02 1.37E-03 2.01E-05 3.49 6.27 13.82
 SCLAV_3814 ECF-subfamily RNA polymerase sigma factor 1.27 1.08 1.71 5.63E-03 1.38E-02 1.94E-04 2.42 2.11 3.27
 SCLAV_4929 Regulatory protein 1.71 1.98 3.90 7.07E-03 1.64E-03 1.49E-06 3.28 3.94 14.92
  1. aOnly some of the most affected genes are shown