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Table 6 NPRS, PKS, and NPRS-PKS hybrid clusters in the X. innexi genome

From: The insect pathogenic bacterium Xenorhabdus innexi has attenuated virulence in multiple insect model hosts yet encodes a potent mosquitocidal toxin

Location Size (bp) Type Number of A or AT domainsa
XIS1_130014 5139 PKSb 1 AT domain
XIS1_250010 13,755 NRPSc 6 A domains
XIS1_40005 - XIS1_60002 21,138 NPRS 4 A domains
XIS1_170001 - XIS1_190004 21,111 NPRS 6 A domains
XIS1_370002 - XIS1_370004 15,468 NPRS 3 A domains
XIS1_390007 - XIS1_400001 15,519 NPRS 5 A domains
XIS1_450016 2997 NRPS 1 A domain
XIS1_460014 7323 NPRS 2 A domains
XIS1_460105 - XIS1_460116 44,193 Hybridd 6 A domains and 2 AT domains
XIS1_480023 - XIS1_480027 23,055 Hybrid 3 A domains and 1 AT domain
XIS1_600036 3060 NRPS 1 A domain
XIS1_660020 - XIS1_660029 21,609 Hybrid 3 A domains and 1 AT domain
XIS1_1050018 - XIS1_1050019 3366 NRPS 1 A domain
XIS1_1690009 - XIS1_1690010 23,319 NRPS 7 A domains
XIS1_1700078 11,811 NRPS 3 A domains
XIS1_1750018 - XIS1_1750021 44,826 NRPS 13 A domains
  1. aA domain; Adenylation domain, AT domain; Acyltransferase domain predicted by antiSMASH
  2. bPKS; Polyketide synthase
  3. cNRPS; Non-ribosomal peptide synthetase
  4. dHybrid; NRPS-PKS hybrid gene