Table 5 Enriched KEEG pathways of DE genes in the Down and Up group using DAVID (89% grain vs. 72% grain)
Term | p value | Molecules |
|---|---|---|
Down Group | ||
Down-regulated genes (n = 45) | ||
bta05150: Staphylococcus aureus infection | 1.5E-04 | FCGR2B, C3, C2, C1QB |
bta04610: Complement and coagulation cascades | 2.9E-04 | A2M, C3, C2, C1QB |
Up-regulated genes (n = 22) | ||
bta04660: T cell receptor signaling pathway | 9.34E-03 | CD3D, CD3G, FOS |
Up Group | ||
Down-regulated genes (n = 163) | ||
bta04110:Cell cycle | 1.07E-05 | PLK1, CCNA2, ESPL1, CDC20, PTTG1, CCNB1, |
bta00010:Glycolysis/Gluconeogenesis | 2.02E-02 | GAPDH, LDHB, ENO2, ENO1 |
bta04068:FoxO signaling pathway | 4.35E-02 | PLK1, MAPK11, BNIP3, CCNB1, CCNB2 |
bta04115:p53 signaling pathway | 4.37E-02 | GTSE1, RRM2, CCNB1, CCNB2 |
bta04978:Mineral absorption | 4.48E-02 | SLC26A6, MT1E, MT2A |
Up-regulated genes (n = 122) | ||
bta00380: Tryptophan metabolism | 2.77E-02 | AOX1, CYP1A1, CYP1B1 |
bta00830:Retinol metabolism | 3.00E-02 | CYP1A1, ADH6, AOX1 |
bta00982:Drug metabolism - cytochrome P450 | 3.73E-02 | ADH6, AOX1, FMO5 |
bta00980:Metabolism of xenobiotics by cytochrome P450 | 4.52E-02 | CYP1A1, ADH6, CYP1B1 |