Table 4 Candidate vaccine targets for ZEBOV. These are completely conserved sequences and predicted to be HLA supertype-restricted
From: Mapping HLA-A2, -A3 and -B7 supertype-restricted T-cell epitopes in the ebolavirus proteome
Protein | Position | Epitope | Supertype specificity |
|---|---|---|---|
NP | 150 | FLSFASLFL | A2 |
265 | HPLARTAKV | B7 | |
311 | GLFPQLSAI | A2 | |
313 | FPQLSAIAL | B7 | |
404 | KLTEAITAA | A2 | |
VP40 | 73 | FILEAMVNV | A2 |
"Post-295 GP" | 580 | RTFSILNRK | A3 |
588 | KAIDFLLQR | A3 | |
667 | ALFCICKFV | A2 | |
VP30 | 171 | LTLCAVMTR | A3 |
L | 45 | KLPKHIYRL | A2 |
293 | KIIKFLEPL | A2 | |
409 | CVFKYSIAK | A3 | |
568 | YPTRNVQTL | B7 | |
580 | LLADGLAKA | A2 | |
780 | TSACGIFLK | A3 | |
786 | FLKPDETFV | A2 | |
795 | HSGFIYFGK | A3 | |
999 | KLINTLFHA | A2 | |
1024 | TPVMSRFAA | B7 | |
1316 | FQNVINYAV | A2 | |
1208 | KPKCPSAAL | B7 | |
1453 | TTHFLTYPK | A3 | |
1494 | YLTTQIHNL | A2 | |
1511 | KPTFKHASV | B7 | |
1816 | KLDEVLWEI | A2 | |
1979 | APFFATGYL | B7 | |
2004 | LTNFLSTTR | A3 | |
2192 | KLIERLTGL | A2 | |
2202 | SLFPDGLYR | A3 |