Fig. 6
From: Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development
The proposed schematic diagram of the fate decision and differentiation of LSPCs. From E11.5 to neonatal, the increased expression of hepatic- or biliary-related genes indicates an elevated hepatocyte or cholangiocyte signature in LSPCs. Black arrows indicate the observed developmental processes in our data, while grey arrows indicate the putative developmental steps. “(1)” and “(2)” denote two possible stages where the fate decisions of LSPCs occur