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Fig. 4 | BMC Genomics

Fig. 4

From: Estrogen exposure overrides the masculinizing effect of elevated temperature by a downregulation of the key genes implicated in sexual differentiation in a fish with mixed genetic and environmental sex determination

Fig. 4

Quantitative real time PCR validation results for genes related to testis differentiation (a-c): anti-Müllerian hormone (amh), doublesex- and mab-3-related transcription factor 1 (dmrt1) and tescalcin (tesc); (d) cholesterol import: steroidogenic acute regulatory protein (star); ovarian differentiation (e-h): gonadal isoform of aromatase (cyp19a1a), SRY-related HMG-box transcription factor SOX17 (sox17), Wnt inducible signaling pathway protein 1 (wisp1), and vasa protein (vasa); (i) the neural isoform of aromatase (cyp19a1b), and (j) insulin-like growth factor 1 (igf1). Asterisks indicate significant statistical differences between groups (* = P < 0.05, ** = P < 0.01, *** = P < 0.001)

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